00 INTRODUCTION Hematoxylin-Eosin stain (H&E stain) is one of the main tissue stains used in histology. It is the most widely used stain in medical diagnosis and is often the gold standard in histopathology. H&E is the combination of two histological stains: hematoxylin and eosin. Nuclei stained with hematoxylin display […]
Bio ink development
20 posts
00 Introduction Thermoplastic polyurethanes (TPU) are a category of materials broadly used for biomedical purposes thanks to their biocompatibility, elasticity and strength. Among the different manufacturing techniques, 3D printing technology has attracted significant attention for the production personalized TPU-based medical devices over the last decade. The preference of this technique […]
+10 INTRODUCTION Alginate, also known as alginic acid, is a natural polysaccharide found in brown algae. It has a linear copolymer structure comprised of homopolymeric blocks of (1→4)-linked β-D-mannuronate and α-L-guluronate residues. Given the similarity of its chemical structure to polysaccharides naturally present in the extracellular matrix of human tissues, […]
00 INTRODUCTION Gelatin hydrogels have attracted significant attention in the field of regenerative medicine, and more specifically, in their use as wound dressings and artificial tissue replacements. Among the different photo-crosslinkable gelatin materials, gelatin methacryloyl (GelMA) hydrogels display a series of advantages, such as good biocompatibility (including biosafety and biological […]
+30 INTRODUCTION Hydrogels are at the forefront of 3D bioprinting and tissue engineering. However, the wide variety of choices available, and the diverse physicochemical nature of the biomaterials comprising the hydrogels, complicate the selection of the most adequate formulation for each specific application. The purpose of this method is to […]
+10 INTRODUCTION Collagen is the most abundant structural protein in the extracellular matrix (ECM), accounting for 30% of the total body protein content in humans. Amongst the 28 types of collagen that have been already identified, collagen type I is the most abundant by far, playing its most prominent functional […]
+10 INTRODUCTION Alginate is a FDA-approved natural polysaccharide extracted from brown algae with multiple applications in the food, cosmetic, and pharmaceutical industries. Its outstanding features including high biocompatibility, ease of gelation, tailorable rheological properties and degradation kinetics make it ideal for 3D bioprinting applications. Alginate hydrogels can be ionically crosslinked […]
+10 Naturally derived hydrogels from decellularized tissues have a remarkable potential for clinical translation. They have the advantage of providing the cells with all the necessary instructions for their growth and differentiation. PRODUCT OVERVIEW: HumaMatrix is one of the first commercially available native human-derived extracellular matrix (ECM) products. HumaMatrix is […]
+20 To work correctly with the Biosafety Cabinet (BC) it is necessary to follow a series of guidelines before, during and after a certain procedure. A. Before starting the procedure – The operation of the BC must be known. The Instruction Manual must be available to the user. – Activate […]
+50 ABSTRACT 3D bioprinting has recently emerged as a crucial technology in tissue engineering, yet there are still challenges in selecting materials to obtain good print quality. Therefore, it is essential to study the influence of the chosen material (i.e., bioink) and the printing parameters on the final result. The […]