00 INTRODUCTION Gelatin hydrogels have attracted significant attention in the field of regenerative medicine, and more specifically, in their use as wound dressings and artificial tissue replacements. Among the different photo-crosslinkable gelatin materials, gelatin methacryloyl (GelMA) hydrogels display a series of advantages, such as good biocompatibility (including biosafety and biological […]
3D bioprinting technology
40 posts
00 INTRODUCTION Working in sterile conditions is key for culturing our scaffolds in aseptic conditions and avoiding contamination. In a 3D Bioprinting protocol we have many sources of contamination, the biomaterial, the cells itself or the 3D bioprinting protocol. The scaffolds with or without cells have the same requirements in […]
+30 INTRODUCTION Type I collagen is the most abundant type of collagen in the human body, as a major structural matrix protein in skin and many other tissues including bone, tendon and fibrous connective tissues. ColBioink is a sterile solution of highly purified collagen type I from porcine origin that […]
+30 INTRODUCTION Hydrogels are at the forefront of 3D bioprinting and tissue engineering. However, the wide variety of choices available, and the diverse physicochemical nature of the biomaterials comprising the hydrogels, complicate the selection of the most adequate formulation for each specific application. The purpose of this method is to […]
+10 INTRODUCTION Collagen is the most abundant structural protein in the extracellular matrix (ECM), accounting for 30% of the total body protein content in humans. Amongst the 28 types of collagen that have been already identified, collagen type I is the most abundant by far, playing its most prominent functional […]
+10 INTRODUCTION Alginate is a FDA-approved natural polysaccharide extracted from brown algae with multiple applications in the food, cosmetic, and pharmaceutical industries. Its outstanding features including high biocompatibility, ease of gelation, tailorable rheological properties and degradation kinetics make it ideal for 3D bioprinting applications. Alginate hydrogels can be ionically crosslinked […]
+20 In this method we briefly explain the main steps to calibrate and configure different fillings in the scaffold using the REGEMAT3D designer. (Please note the image below is an animated one, please wait until it starts again). Configuration of the Gcode: Configuration of the filling: pre […]
+20 To work correctly with the Biosafety Cabinet (BC) it is necessary to follow a series of guidelines before, during and after a certain procedure. A. Before starting the procedure – The operation of the BC must be known. The Instruction Manual must be available to the user. – Activate […]
+50 ABSTRACT 3D bioprinting has recently emerged as a crucial technology in tissue engineering, yet there are still challenges in selecting materials to obtain good print quality. Therefore, it is essential to study the influence of the chosen material (i.e., bioink) and the printing parameters on the final result. The […]
+20 Introduction Electrically conductive thermoplastic elastomers hold idyllic attributes for the 3D printing of flexible and electroconductive scaffolds with applications in electronics, electromagnetics and computer industries. Beyond these applications, they have a tremendous potential in the biomedical sector. Due to their enhanced biocompatibility, they can be used as biosensors and […]