+20 “Stability for Long Lasting Support.” Introduction X Stable INX© is a synthetic shear thinning, cell-interactive scaffold ink. X Stable INX allows an easy printing process thanks to its shear thinning behavior, as schematically presented in Figure 1a. At high shear rates, it exhibits a low viscosity which is favorable […]
3D bioprinting technology
32 posts
+20 Introduction Material extrusion is an additive manufacturing technique that uses a continuous filament of thermoplastic or composite material to construct 3D parts. Filament-based material extrusion is the most common practice in the 3D printing community. However, it’s not necessary for extrusion to only work with filament. In fact, pellet […]
+30 The printing process of FILAMENT-Oss is carried out by a Fused Filament Fabrication process (FFF/FDM). As any other Additive Manufacturing technique, the FFF creates a physical 3D object from a digital model (usually a CAD representation) which is sliced in layers at consecutive height levels. The process requires of […]
+5-1 The biofabrication technique comprises two processes for every volume: first, the fused deposition of the thermoplastic polymer to obtain the scaffold and second, the injection of the bioink and CaCl2 solution to fill the printed scaffold. Firstly, commercial non-medical grade PLA (1.75 mm filament) was used and it […]
+100 Introduction: Injuries to the knee meniscus commonly lead to osteoarthritis. Current therapies for meniscus regeneration, including meniscectomies and scaffold implantation, do not achieve complete functional tissue regeneration. This has led to increased interest in cell and gene therapies and tissue engineering approaches to meniscus regeneration. The implantation of a […]
+40 Introduction Hypoxia is a common characteristic of many solid tumors that has been associated with tumor aggressiveness. Limited diffusion of oxygen generates a gradient of oxygen availability from the blood vessel to the interstitial space and may underlie the recruitment of macrophages fostering cancer progression. However, the available data […]
+110 In recent years, the development and use of biomaterials has undergone a great advance because they have made it possible to improve people’s life expectancy, improve surgical techniques and, on the other hand, successfully develop implants and medical devices capable of working properly in contact with tissues of the […]
+30 In this method we describe the parameters to FDM bioprint scaffolds for Bone regeneration Composed by of 80% PCL that had a MW 80,000 (Polysciences Europe, Hirschberg an der Bergstraße, Germany) and 20% of the synthetic biphasic calcium phosphate bone substitute material (BCP) (synprint, ScientiFY GmbH, Berlin, Germany) with […]
+30 3cc X- gel-Ma INX ready-to-use syringes were loaded and the bioprinted using the V1 REGEMAT3D bioprinter, equipped with the REGEMAT3D Designer Version 1.5, REGEMAT3D, Granada, Spain. Grids having a 10mmx10mm in width and length and 1mmx1mm as pore size were printed directly on the glass for testing purposes. The […]
+30 CNF Nanocellulose gels (2 wt %) were used as inks for 3D printing. The 3D printing was performed with a Regemat3D bioprinter (version 1.0), equipped with the Regemat3D Designer (version 1.8, Regemat3D, Granada, Spain). Grids having a diameter of 20 mm and a height of 2 mm were printed […]