+10 Hydroxypropyl methylcellulose METHOCEL ™ K4M (Colorcon Ltd., UK) was used as hydrophilic polymer to prepare drug-loaded hydrogels for IVF. Anhydrous theophylline (Acofarma, Spain) has been used as a model drug. HPMC (1% w/v) gel was prepared by adding powdered HPMC into 100 ml of hot water (90 °C) and […]
Drug discovery and development
15 posts
+20 Introduction Material extrusion is an additive manufacturing technique that uses a continuous filament of thermoplastic or composite material to construct 3D parts. Filament-based material extrusion is the most common practice in the 3D printing community. However, it’s not necessary for extrusion to only work with filament. In fact, pellet […]
+20 Introduction Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers enclosing an aqueous core. Nontoxic and biodegradable liposomes are useful tools to package both hydrophilic and hydrophobic biomolecules (including therapeutic agents) that may be further incorporated into target cells to elicit functional changes. Extensive research is […]
+30 3cc X- gel-Ma INX ready-to-use syringes were loaded and the bioprinted using the V1 REGEMAT3D bioprinter, equipped with the REGEMAT3D Designer Version 1.5, REGEMAT3D, Granada, Spain. Grids having a 10mmx10mm in width and length and 1mmx1mm as pore size were printed directly on the glass for testing purposes. The […]
+30 Introduction Organ-on-a-chips are defined as physiological organ biomimetic systems built on microfluidic devices. By combining cell biology, engineering and biomaterial technology, the microenvironment of the chip is able to simulate tissue interfaces and mechanical stimulation of the native organ. They are in the list of top 10 emerging technologies […]