Naturally derived hydrogels from decellularized tissues have a remarkable potential for clinical translation. They have the advantage of providing the cells with all the necessary instructions for their growth and differentiation.
HumaMatrix is one of the first commercially available native human-derived extracellular matrix (ECM) products. HumaMatrix is isolated from nutrient-rich human tissue sourced strictly from American Association of Tissue Banks (AATB) and Organ Procurement Organizations (complying with FDA 21 CFR Part 1271 requirements), following a proprietary manufacturing method to preserve native matrix proteins including collagen, elastin, laminin, glycosaminoglycans and many others, as well as growth factors. INTENDED USE: HumaMatrix is an alternative to Matrigel and it is ideal for many applications including the coating of tissue culture surfaces and the preparation of bioinks for 3D bioprinting. Among other applications, HumaMatrix can be specifically used for the culture of organoids under more realistic 3D microenvironments. Its human origin avoids clinical concerns associated with the use of xeno-derived biomaterials while enhances the relevance and clinical translation of the results.